Pharmacogenetic Testing For Avoiding Adverse Drug Effects

According to Waleed Alabsi, Pharmacogenomics refers to the study of how the genetic makeup of a person affects their response to medications. This field done by Youscript System combines

According to Waleed Alabsi, Pharmacogenomics refers to the study of how the genetic makeup of a person affects their response to medications. This field done by Youscript System combines pharmacology and genomics to come up with effective and safe medications that are personalized and tailored to a person’s genetic makeup.

Adverse drug reactions contribute to a significant number of hospitalizations and death. Researchers are discovering how inherited differences in genes can affect a body’s response to medication. Genomics is used to identify whether a medication will work in a patient or it will result in an adverse drug reaction.


A significant cause of death and serious illness in patients according to Youscript is due to adverse drug reactions and causes difficulties in the pharmaceutical industry during drug development. Adverse reactions are classed as idiosyncratic reactions which are not caused by drug concentrations but due to unusual patient phenotype. Serious adverse drug reactions are classified as type A or B.

Waleed Alabsi says that Idiosyncratic adverse reactions are believed to affect different organs like the liver, skin, heart, and muscle, and kidney. In some drugs, hypersensitivity reactions can occur. Looking at drug withdrawals, the biggest number of compounds withdrawn from the market was because of either hepatotoxicity or toxicity affecting cardiac function. When the lever is affected by adverse drug reactions it shows heterogeneity in their phenotypic effect. These reactions are referred to as drug-induced liver injury (DILI). 10% of these hepatotoxic adverse drug reactions have the potential to progress to liver failure which can be resolved through a liver transplant.

According to Waleed Alabsi, an important feature of serious adverse drug reactions is genetic susceptibility. There is considerable interest that the development of genetic tests identifying all those at risk of adverse drug reactions before prescription might lead to the development of valuable drugs.

Pharmacogenomic approaches used to identify causative genes:

Research on pharmacogenomics by Youscript to identify genes that contribute to susceptibility to adverse drug reactions has involved case-control association studies through candidate feen approach or genome-wide association (GWA) analysis. Developments in GWA studies have contributed to considerable progress in complex disease genomics. This is considered the most appropriate approach to use in identifying causative genes in adverse drug reactions.

According to Waleed Alabsi, a few reasons have been identified for this. The genetic risk factors identified have large effect sizes and are generally found in biologically obvious genes. The advantage of GWA studies is their open approach where all gene variations are looked into. This advantage has led to the discovery of entirely novel associations that would otherwise have been unlikely to be predicted through candidate gene approaches. When detecting small defects, GWA is particularly valuable though the limitation with most studies on adverse drug reactions is that the number of study cases is small. Assembling large uniform cohorts can be challenging since the genetic risk factors for adverse drug reactions are drug-specific and not simply end-organ-specific.

Waleed Alabsi says that it is unlikely that GWA studies will identify all genetic risk factors that cause adverse drug reactions. There are rare variants that can only be detected by sequencing studies. Through exome sequencing where all coding of genes is a sequence, significant progress has been made in some diseases. This type of sequencing by the Youscript System has been most valuable in detecting variants in rare diseases that show Mendelian inheritance rather than in complex diseases. That said there have been some exceptions reported in the fields of infectious disease and type II diabetes. Where regulatory sequences are determined in whole-genome sequencing, it s necessary to provide sufficient sensitivity to spot rare variants that are relevant to adverse drug reactions.

Waleed Alabsi describes an adverse drug event as an injury resulting from a medical intervention related to a drug. This can be in the form of allergic reactions, medication errors, overdoses, and adverse drug reactions.

Waleed Alabsi describes an adverse drug event as an injury resulting from a medical intervention related to a drug. This can be in the form of allergic reactions, medication errors, overdoses, and adverse drug reactions. A study published in the Journal of Patient Safety found that approximately 13% of 30-day hospital re-admissions were caused by ADEs. Out of those, more than 80% were serious, and close to 93% were preventable.

There are reasons why patients have adverse drug events. Here’s a look into them.

  1. Errors in prescriptions

A research study conducted into 30-day readmissions found that half of all readmissions were caused by drug events which were attributed to patients receiving the wrong prescription. This is especially the case in patients who are analgesics, diuretics, and antithrombotics.YouScript technology helps doctors avoid prescribing the wrong medication.

2. Reconciliation errors

Waleed Alabsi says that medication reconciliation is a major issue of concern for patients taking multiple medications. A report on Hospital National Patient Safety Goals by the Joint Commission identified medical reconciliation as a top priority. Multiple medications could pose a risk that some of these treatments could interact badly resulting in health issues for the patient.

3. Patient errors

YouScript System ensures that chances of patients misunderstanding their doctor’s instructions, fail to remember how much drug they have taken, or mistakenly take too much or too little of their prescribed drugs are avoided. A patient may also forget to inform their physician about all the medications they are on resulting in negative side effects.

Common Medications That Cause Adverse Events:

While an ADE can be seen to occur with any medication, according to Waleed Alabsi, some common medications often bring issues.

These medications include:

Inhalers – Common mistakes while using the inhaler include not assembling the inhaler correctly and going through the whole process of inhaler use. Incorrect use of an inhaler can result in the patient ending up back in the hospital.

Anticoagulants (Blood Thinners) – These medications are classified as high risk. They can be life-saving for patients with heart disease while carrying the risk of causing bleeding and hospital readmission

Diabetes Medications – Patients can have an ADE when taking insulin medications by taking either too much or too little.

Pain Medications (Opioids) – Opioids are used to manage pain. The regular use of opioids even when prescribed by a medical professional can lead to addiction and misuse can overdose or even death.

How to Prevent Adverse Drug Events

Waleed Alabsi recommends that patients do the following to prevent adverse drug events:

  1. YouScrpit helps take an inventory of every drug you are taking and how much you take it.
  2. Include over-the-counter medications that you take regularly. Many of these drugs can have adverse reactions when combined with prescription drugs.
  3. Ensure that you follow the instructions given by your doctor.
  4. It is advisable to consider enrolling in the Waleed Alabsi rehabilitation program. It has many benefits like having a team of rehab professionalsthat will help manage your medications, keep a track of how many medications you have and when you should take them. They will also ensure that your medical regime is safe and appropriate making sure you are aware of any potential risks and how to minimize them.
  5. YouScript Systemensures that drug labeling is done well to avoid overdosing or under-dosing.
  6. Alcohol should never be consumed while a patient is under medication.
  7. Some medications require one to eat food before taking the drug while other medications require a patient not to consume food. It’s important to adhere to this as instructed.
  8. Be aware of previous drug reactions and look at the label on your current medication for any components that can cause a reaction.
  9. Waleed Alabsia dvises patients not to take Over-The-Counter medications together with vitamins.

YouScript introduces a huge database for patient care with pharmacogenetic testing to offer a clear understanding of an individual’s drug responses.

With YouScript, doctors and physicians can prescribe the right medicines to patients, lowering the adverse health risks. The company synthesizes all drug responses to improve the point of care. Since doctors do not have enough time to understand patient’s personalized medicine responses, this database fulfils the gap and improves the practices of prescribing the medicines. Waleed Alabsi, the CEO of the Alabsi Group, is partnering with YouScript with an aim to improve the health care needs of people.

We are there to support the right decision that doctors make for the health of patients. What makes us unique is our continuous efforts to make the drug database effective for the users. We always update our work with new medicines and researches to include the best and most effective things that meet our goal. We also perform pharmacogenetic testing that helps us improve the personal care approach.

What is pharmacogenetic testing?

Pharmacogenetic testing checks the genetic variants, especially record their response to drugs. The variants in genes are also known for drug-metabolizing enzymes, drug targets, and more. This kind of testing checks whether the gene is heterozygous or homozygous. Based on these details, YouScript can predict individual drug responses very well.

When has the pharmacogenetic test been conducted?

Doctors can prescribe such tests at any point during the treatment. The gene variants in regards to drug responses reveal many details regarding individual health. It makes the treatment even more potent, helping patients get rid of complications easily.

The test also takes care of the other factors and combines data of a patient’s clinical information, age, weight, height, and other drug histories. Doctors, using the information from the test, can decide the dose of the medicines and other things. Along with this test, doctors also need therapeutic drug monitoring for their health.

Pharmacogenetic testing for a specific gene is done once since a person’s genetic structure does not change. For evaluating the drug response, a single gene or multi genes have been tested. Pharmacogenetic testing is conducted before starting drug therapy. YouScript concentrated on pharmacogenetic testing for health. We are clinically validated for reducing adverse drug events.

Our huge database contains details that help pharmacists and doctors enhance the treatment goals with the right medicines. When doctors have a clear understanding of an individual’s drug response, prescribing medicines can be easier for him/her.

It concentrates on a few essential factors, including:

  1. Drug-gene and drug-drug interaction
  2. Populations and patient’s view

Since every patient is unique in terms of drug responses, our database can introduce the best treatment approaches. YouScript is one of the partners of the Alabsi Group led by Waleed Alabsi, who helps businesses meet their goals, offering the best support. Please contact us for more details.

YouScript is a personalized medication management system offering precision in prescribing medicines.

YouScript synthesizes every drug response to help doctors and pharmacists offer a better point of care to patients. Our technology helps everyone associated with the medical industry. Our system is clinically approved and offers precision in prescribing medicines. Many health care organizations have already connected with us and implement our system in their care services. Waleed Alabsi supports YouScript for improving the system of prescribing personalized medication. He is the CEO of the Alabsi Group that helps businesses meet their goals and achievements.

Pharmacogenetic testing also makes our research stronger. Every member of our group belongs from pharmacogenetics, healthcare, technological developments, and we are the trusted partners ofpayersband providers who want to reduce the healthcare cost and offer the best medicines for your health.

YouScript will be the right solution for different parts of the health care field, including health plans, healthcare organizations, and more. We eliminate the barriers in a personalized medication system. We concentrate on the core of the study and successfully eliminate the risks associated with the commonly prescribed drug responses.

We also check the effects of the drugs on a patient’s metabolism capacity. You will also get a high-level drug interaction alert when using our system. Our pharmacogenetic testing with the medication management software is available for everyone. To know more details, you can contact Alasbi Group or us.

With our software application, you can also predict side-effects of medicines since we bring you the metabolic drug responses for your health. We aim at a few factors, including minimizing the side effects, reducing adverse drug events, inappropriate patient care, and more.

The benefits of using our systems:

A large number of health problems arose due to the use of wrong drugs on our health. It also increases the prices of health care. Our system concentrates on the root cause of the problem and offers the best solution.

Health care organizations can also prescribe the medicines confidently, eliminating the side effects. We partner with the Alasbi Group, a reputed organization that helps business to meet their demands. You will get quality services from us. Besides, you can contact us any time you need any help.

Every drug has a risk of side effects in some forms. When doctors and pharmacists get complete knowledge about the medicines and their responses to human health, they can offer the best care.

We aim to enhance the medical field, and we perform our best to develop this software system. You can contact us for more details. YouScript has partnered with the Alabsi Group led by Mr.Waleed Alabsi to help doctors and medical professionals in prescribing the right medicine.

YouScript is a platform for prescribing precision medicines, defining all side effects related to drug responses and interactions on our health.

YouScript has undertaken a novel approach for the healthcare field to make prescribing medicines even more perfect and accurate for a treatment. We have concentrated on the evidence regarding drug response and utilizes pharmacogenetic testing to make the evidence-based decision for your health. Doctors and pharmacists can use our data to decide on the medicines for specific treatments. Mr.Waleed Alabsi promotes YouScript to enhance patient care as YouScript presents comprehensive detail regarding the drug response.

We aim to reduce healthcare costs by offering better medicines for your health. We are the trusted partners of healthcare organizations, providers, and payers.

We help everyone from the healthcare field:

We partner with health plans, health care organizations, healthcare providers, and pharmacists to offer better treatments. We address the problems related to personalized medication management, eliminating wrong drugs that may cause side effects on patients’ health.

Our evidence-based study includes everything, including

  1. The commonly prescribed drugs and their effects on our health
  2. The impacts of drugs on patients
  3. Drug interaction alert

We bring you the details about the drug metabolism so that everyone can understand the medicines and their requirement for health. Our wide database is created to minimize side effects, improve patient care, and save patients time and money. Our precision prescribing platform reduces a huge cost by reducing the adverse impacts of prescription drugs.

We concentrate on every barrier in prescribing medicines. By reducing adverse drug events, we are successful in reducing the costs and the number of hospitalization. To make our research even more strong, we also invest in pharmacogenetic testing to check different drug interactions. This process helps us find out the possible side effects to eliminate the problems. With us, doctors can confidently prescribe drugs that bring the best effects on patient’s care. Our platform helps doctors note different drug responses for your health. So, prescribing the wrong drugs will no longer happen.

Why are we for?

Every drug has a risk of side effects, and every patient will experience this problem. Since pharmacists are not aware of the origin of side effects, it may cause adverse drug events. We concentrate on drug interactions, including drug-drug, drug-gene, multi-drug-gene combinations, to reveal an in-depth knowledge about the side effects. Our platform provides clear data regarding different drugs.

If you want more details and want to use our system, you must visit YouScript. We will be happy to clear your all doubts. The Alabsi Group, led by Waleed Alabsi, promotes YouScript to the health care fields that help patients get the right medicines for their health issues.

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